Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation
Identifieur interne : 002A07 ( Main/Exploration ); précédent : 002A06; suivant : 002A08Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation
Auteurs : Gaël Piton [France] ; Gilles Capellier [France]Source :
- Critical Care [ 1364-8535 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- physiopathologie : Intestin grêle.
- sang : Citrulline, Jeûne.
- Absorption intestinale, Femelle, Humains, Maladie grave, Mâle.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Citrulline.
- blood : Fasting.
- physiopathology : Intestine, Small.
- Critical Illness, Female, Humans, Intestinal Absorption, Male.
Abstract
In a recent issue of
Url:
DOI: 10.1186/s13054-015-0881-1
PubMed: 25930068
PubMed Central: 4416254
Affiliations:
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Le document en format XML
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type="city">Besançon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff2">Research Unit EA 3920 and SFR FED 4234, University of Franche Comté, Besançon, 25030 France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Research Unit EA 3920 and SFR FED 4234, University of Franche Comté, Besançon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Franche-Comté</region><settlement type="city">Besançon</settlement></placeName></affiliation></author><author><name sortKey="Capellier, Gilles" sort="Capellier, Gilles" uniqKey="Capellier G" first="Gilles" last="Capellier">Gilles Capellier</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Medical Intensive Care Unit, University Hospital, Besançon, 25030 France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Medical Intensive Care Unit, University Hospital, Besançon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Franche-Comté</region><settlement type="city">Besançon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff2">Research Unit EA 3920 and SFR FED 4234, University of Franche Comté, Besançon, 25030 France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Research Unit EA 3920 and SFR FED 4234, University of Franche Comté, Besançon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Franche-Comté</region><settlement type="city">Besançon</settlement></placeName></affiliation><affiliation><nlm:aff id="Aff3">Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Clayton, VIC 3168 Australia</nlm:aff><wicri:noCountry code="subfield">VIC 3168 Australia</wicri:noCountry></affiliation></author></analytic><series><title level="j">Critical Care</title><idno type="ISSN">1364-8535</idno><idno type="eISSN">1466-609X</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Citrulline (blood)</term><term>Critical Illness</term><term>Fasting (blood)</term><term>Female</term><term>Humans</term><term>Intestinal Absorption</term><term>Intestine, Small (physiopathology)</term><term>Male</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Absorption intestinale</term><term>Citrulline (sang)</term><term>Femelle</term><term>Humains</term><term>Intestin grêle (physiopathologie)</term><term>Jeûne (sang)</term><term>Maladie grave</term><term>Mâle</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Citrulline</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Fasting</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Intestin grêle</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Intestine, Small</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Citrulline</term><term>Jeûne</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Critical Illness</term><term>Female</term><term>Humans</term><term>Intestinal Absorption</term><term>Male</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Absorption intestinale</term><term>Femelle</term><term>Humains</term><term>Maladie grave</term><term>Mâle</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In a recent issue of <italic>Critical Care</italic>, Poole and colleagues found that plasma citrulline concentration and glucose absorption were reduced in 20 critically ill patients compared with 15 controls; however, the authors found no correlation between these two variables. This study highlights the question of the accuracy of plasma citrulline for assessing small bowel function in critically ill patients. Future studies should take into account the type of intestinal failure considered, the particular metabolism of citrulline, the time of plasma citrulline measurement, as well as the range of citrullinemia considered.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Poole, A" uniqKey="Poole A">A Poole</name></author><author><name sortKey="Deane, A" uniqKey="Deane A">A Deane</name></author><author><name sortKey="Summers, M" uniqKey="Summers M">M Summers</name></author><author><name sortKey="Fletcher, J" uniqKey="Fletcher J">J Fletcher</name></author><author><name sortKey="Chapman, M" uniqKey="Chapman M">M Chapman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khadaroo, Rg" uniqKey="Khadaroo R">RG Khadaroo</name></author><author><name sortKey="Marshall, Jc" uniqKey="Marshall J">JC Marshall</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Deitch, Ea" uniqKey="Deitch E">EA Deitch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Curis, E" uniqKey="Curis E">E Curis</name></author><author><name sortKey="Nicolis, I" uniqKey="Nicolis I">I Nicolis</name></author><author><name sortKey="Moinard, C" uniqKey="Moinard C">C Moinard</name></author><author><name sortKey="Osowska, S" uniqKey="Osowska S">S Osowska</name></author><author><name sortKey="Zerrouk, N" uniqKey="Zerrouk N">N Zerrouk</name></author><author><name sortKey="Benazeth, S" uniqKey="Benazeth S">S Bénazeth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crenn, P" uniqKey="Crenn P">P Crenn</name></author><author><name sortKey="Coudray Lucas, C" uniqKey="Coudray Lucas C">C Coudray-Lucas</name></author><author><name sortKey="Thuillier, F" uniqKey="Thuillier F">F Thuillier</name></author><author><name sortKey="Cynober, L" uniqKey="Cynober L">L Cynober</name></author><author><name sortKey="Messing, B" uniqKey="Messing B">B Messing</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crenn, P" uniqKey="Crenn P">P Crenn</name></author><author><name sortKey="Vahedi, K" uniqKey="Vahedi K">K Vahedi</name></author><author><name sortKey="Lavergne Slove, A" uniqKey="Lavergne Slove A">A Lavergne-Slove</name></author><author><name sortKey="Cynober, L" uniqKey="Cynober L">L Cynober</name></author><author><name sortKey="Matuchansky, C" uniqKey="Matuchansky C">C Matuchansky</name></author><author><name sortKey="Messing, B" uniqKey="Messing B">B Messing</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Piton, G" uniqKey="Piton G">G Piton</name></author><author><name sortKey="Manzon, C" uniqKey="Manzon C">C Manzon</name></author><author><name sortKey="Cypriani, B" uniqKey="Cypriani B">B Cypriani</name></author><author><name sortKey="Carbonnel, F" uniqKey="Carbonnel F">F Carbonnel</name></author><author><name sortKey="Capellier, G" uniqKey="Capellier G">G Capellier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Piton, G" uniqKey="Piton G">G Piton</name></author><author><name sortKey="Manzon, C" uniqKey="Manzon C">C Manzon</name></author><author><name sortKey="Monnet, E" uniqKey="Monnet E">E Monnet</name></author><author><name sortKey="Cypriani, B" uniqKey="Cypriani B">B Cypriani</name></author><author><name sortKey="Barbot, O" uniqKey="Barbot O">O Barbot</name></author><author><name sortKey="Navellou, J C" uniqKey="Navellou J">J-C Navellou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Piton, G" uniqKey="Piton G">G Piton</name></author><author><name sortKey="Belon, F" uniqKey="Belon F">F Belon</name></author><author><name sortKey="Cypriani, B" uniqKey="Cypriani B">B Cypriani</name></author><author><name sortKey="Regnard, J" uniqKey="Regnard J">J Regnard</name></author><author><name sortKey="Puyraveau, M" uniqKey="Puyraveau M">M 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Fichet</name></author><author><name sortKey="Pene, F" uniqKey="Pene F">F Pène</name></author><author><name sortKey="Marx, J S" uniqKey="Marx J">J-S Marx</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pan, L" uniqKey="Pan L">L Pan</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name></author><author><name sortKey="Li, W" uniqKey="Li W">W Li</name></author><author><name sortKey="Li, N" uniqKey="Li N">N Li</name></author><author><name sortKey="Li, J" uniqKey="Li J">J Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Noordally, So" uniqKey="Noordally S">SO Noordally</name></author><author><name sortKey="Sohawon, S" uniqKey="Sohawon S">S Sohawon</name></author><author><name sortKey="Semlali, H" uniqKey="Semlali H">H Semlali</name></author><author><name sortKey="Michely, D" uniqKey="Michely D">D Michely</name></author><author><name sortKey="Devriendt, J" uniqKey="Devriendt J">J Devriendt</name></author><author><name sortKey="Gottignies, P" uniqKey="Gottignies P">P Gottignies</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cynober, L" uniqKey="Cynober L">L Cynober</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coste, J" uniqKey="Coste J">J Coste</name></author><author><name sortKey="Pouchot, J" uniqKey="Pouchot J">J Pouchot</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>France</li></country><region><li>Bourgogne-Franche-Comté</li><li>Franche-Comté</li></region><settlement><li>Besançon</li></settlement></list><tree><country name="France"><region name="Bourgogne-Franche-Comté"><name sortKey="Piton, Gael" sort="Piton, Gael" uniqKey="Piton G" first="Gaël" last="Piton">Gaël Piton</name></region><name sortKey="Capellier, Gilles" sort="Capellier, Gilles" uniqKey="Capellier G" first="Gilles" last="Capellier">Gilles Capellier</name><name sortKey="Capellier, Gilles" sort="Capellier, Gilles" uniqKey="Capellier G" first="Gilles" last="Capellier">Gilles Capellier</name><name sortKey="Piton, Gael" sort="Piton, Gael" uniqKey="Piton G" first="Gaël" last="Piton">Gaël Piton</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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